FGAR Amidotransferase: A Purine Biosynthetic Enzyme with Potential as a Target for Antimicrobial Drugs.

5/8/98


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Table of Contents

FGAR Amidotransferase: A Purine Biosynthetic Enzyme with Potential as a Target for Antimicrobial Drugs.

Overview

Rhizobium-Legume Symbiosis Early Steps

Rhizobium-Legume Symbiosis Intermediate Steps

Symbiotic phenotype of Rhizobium purine auxotrophs

The Purine Biosynthetic Pathway

Hypotheses

Symbiosis Research Projects

The Purine Biosynthetic Pathway

An Intriguing Observation

Complementation Analysis

Marker Exchange - Recovery of Mutations

pCOS110 Complementation Groups

pCOS110 Map

The Purine Biosynthetic Pathway

FGAR Amidotransferase

FGAR Amidotransferase Organization

FGAR Amidotransferase Phylogenetic Analysis

PurY as a Third Subunit

PurY as a Third Subunit

Future Work

Lab Members

Author: Jeff Newman

Email: newman@lycoming.edu

Home Page: http://lyco.lycoming.edu/~newman/index.html

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